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Published on: February 4, 2021
Optimum management of elderly patients with calcified aortic stenosis
A Pieter Kappetein1, Martijn van Geldorp, Johanna J M Takkenberg
1Department of Cardio-thoracic Surgery, Erasmus Medical Center, Room Bd 569, PO Box 2040, 3000 CA Rotterdam, The Netherlands. a.kappetein@erasmusmc.nl
Insights
Elderly individuals often develop aortic stenosis. This review covers diagnosis, treatment options like aortic valve replacement, and new minimally invasive techniques for this growing population.
Area of Science:
- Cardiology
- Geriatrics
- Valvular Heart Disease
Background:
- Aging populations are experiencing increased incidence of aortic stenosis.
- Calcific aortic stenosis is a significant health concern in the elderly.
- Early diagnosis and management are crucial for improving outcomes.
Purpose of the Study:
- To review the pathogenesis, diagnosis, and management of calcific aortic stenosis.
- To discuss current treatment modalities, including surgical and emerging minimally invasive aortic valve replacement.
- To identify suitable candidates for novel treatment approaches in elderly patients.
Main Methods:
- Literature review of pathogenesis, diagnosis, and treatment of aortic stenosis.
- Analysis of current guidelines for aortic valve replacement.
- Evaluation of emerging transfemoral and transapical aortic valve implantation techniques.
Main Results:
- Symptomatic severe aortic stenosis necessitates consideration for aortic valve replacement.
- Surgical aortic valve replacement remains the primary treatment.
- Transcatheter aortic valve implantation (TAVI) offers a viable alternative for select elderly patients.
Conclusions:
- Aortic stenosis management requires a tailored approach considering patient age and comorbidities.
- Minimally invasive techniques are expanding treatment options for elderly patients with aortic stenosis.
- Further research is needed to optimize patient selection for emerging aortic valve replacement strategies.
Abstract:
Increased life-expectancy has led to a growing elderly population frequently presenting with aortic stenosis. This review focuses on the pathogenesis of calcific aortic stenosis, diagnosis and possible ways to halt the progression to severe symptomatic aortic stenosis, methods of assessing symptoms and severity, and modalities and timing of aortic valve replacement. At present the treatment of aortic stenosis for the majority of patients is surgical, and any patient with symptomatic severe aortic stenosis should be considered for aortic valve replacement. This article also discusses the role of emerging techniques of closed heart valve implantation either transfemoral or transapical, and which patients might be candidates for these new approaches to the treatment of aortic stenosis in the elderly population.
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