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Microbial complexes in supragingival plaque.

A D Haffajee1, S S Socransky, M R Patel

  • 1Department of Periodontology, The Forsyth Institute, Boston, MA 02115, USA. ahaffajee@forsyth.org

Oral Microbiology and Immunology
|April 12, 2008
PubMed
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Specific microbial communities in supragingival biofilm were identified. These bacterial complexes showed similarities to subgingival plaque and related to periodontal disease parameters.

Area of Science:

  • Microbiology
  • Oral Health
  • Periodontology

Background:

  • Supragingival biofilm harbors complex microbial communities.
  • Understanding these microbial structures is crucial for oral health.
  • Previous research has focused on subgingival plaque, with less known about supragingival associations.

Purpose of the Study:

  • To characterize the microbial communities within supragingival biofilm samples.
  • To identify bacterial species associations in supragingival plaque.
  • To compare supragingival microbial complexes with those in subgingival plaque.

Main Methods:

  • Analysis of 4745 supragingival plaque samples from 187 subjects at baseline.
  • Collection of plaque samples at 1-7 days and 3-24 months post-professional cleaning.

Related Experiment Videos

  • Utilized checkerboard DNA-DNA hybridization to quantify 40 bacterial species.
  • Applied cluster analysis and community ordination to determine microbial associations.

    • Main Results:

    • Six distinct bacterial complexes were identified in baseline supragingival plaque samples.
    • Similar complexes were observed in samples collected 3-24 months post-therapy.
    • Significant shifts in microbial communities occurred during the initial 7 days of plaque redevelopment.
    • Identified complexes correlated with clinical parameters of periodontal disease.

    Conclusions:

    • Specific microbial complexes exist in supragingival plaque, largely mirroring subgingival plaque compositions.
    • Minor differences were noted between supragingival and subgingival microbial complexes.
    • The study elucidated the relationships of previously unclustered bacterial taxa to established complexes.