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Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Related Experiment Video

Updated: Jul 6, 2026

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

The hydroxylapatite-bone interface: 10 years after implant installation.

H C S Beekmans¹, G J Meijer, R Barkhuysen

¹Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Center, The Netherlands.

International Journal of Oral and Maxillofacial Surgery

|April 12, 2008

Summary

This summary is machine-generated.

This study reports a 10-year histological analysis of sinus augmentation using hydroxylapatite (HA) granules and autologous bone. The findings show stable bone contours and minimal HA degradation, supporting its use for dental implant success.

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Area of Science:

Oral surgery
Biomaterials science
Dental implantology

Background:

Sinus augmentation with hydroxylapatite (HA) granules and autologous bone is a common procedure for severely atrophied maxillas.
Long-term histological data on HA-coated dental implants after this procedure is limited.

Observation:

A patient underwent maxillary sinus augmentation using a mixture of HA granules and autologous bone, followed by functional implant loading.
Post-mortem histological analysis was performed on the patient's upper jaw 10 years after the augmentation and implant placement.

Findings:

The augmented region demonstrated stable radiographic and histological contours over 10 years.
Hydroxylapatite granules showed minimal degradation and effectively protected the grafted area from resorption.
The plasma-sprayed HA coating on the dental implants remained intact, with 48% bone-to-implant contact.

Implications:

This case report provides long-term histological evidence supporting the predictability and stability of sinus augmentation with HA and autologous bone for dental implant success.
The findings suggest that HA granules and HA-coated implants are a viable option for complex maxillary reconstructions.
Further long-term studies are warranted to confirm these findings in a larger patient cohort.