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Published on: February 6, 2021
Ocular infections due to anaerobic bacteria in children
1Department of Pediatrics, Georgetown University, Washington, DC, USA.
Insights
Anaerobic bacteria are increasingly found in pediatric infections, particularly ocular infections like conjunctivitis and keratitis. Prompt diagnosis and management are crucial for these often-severe conditions in children.
Area of Science:
- Microbiology
- Pediatrics
- Ophthalmology
Background:
- Anaerobic bacteria are increasingly recognized as significant pathogens in pediatric infections.
- Ocular infections in children can be caused by a variety of anaerobic organisms.
- Adequate recovery methods are essential for identifying anaerobic involvement.
Purpose of the Study:
- To review the microbiology of anaerobic ocular infections in children.
- To outline diagnostic approaches for these infections.
- To discuss current management strategies for pediatric anaerobic eye infections.
Main Methods:
- Literature review of studies on anaerobic bacteria in pediatric ocular infections.
- Analysis of reported anaerobic isolates from conjunctivitis, keratitis, and dacryocystitis.
- Synthesis of information on diagnostic techniques and treatment options.
Main Results:
- Anaerobes were isolated from approximately one-third of children with conjunctivitis, often in pure culture.
- Commonly isolated anaerobes include Clostridium spp., gram-negative anaerobic bacilli, Peptostreptococcus spp., Propionibacterium spp., Prevotella spp., and Fusobacterium spp.
- Anaerobic bacteria are implicated in conjunctivitis, keratitis, and dacryocystitis in children, including contact lens wearers.
Conclusions:
- Anaerobic bacteria play a notable role in pediatric ocular infections.
- Accurate identification and appropriate treatment are vital for successful outcomes.
- This review provides a comprehensive overview for clinicians managing these infections.
Abstract:
The recent increased recovery of anaerobic bacteria from children has led to greater appreciation of the role these organisms play in pediatric infections at all body sites, including the eye. In studies that employed adequate methods for recovery of anaerobes, they were isolated from approximately one-third of the children with conjunctivitis, half of the time in pure culture. The predominant recovered anaerobes were Clostridium spp., gram-negative anaerobic bacilli, and Peptostreptococcus spp. Anaerobic bacteria were also recovered from patients who wore contact lenses and developed conjunctivitis, and were reported in cases of keratitis. The most frequently recovered anaerobes were Propionibacterium spp., Peptostreptococcus spp., Clostridium spp., Prevotella spp., and Fusobacterium spp. The most frequently recovered anaerobes from dacryocystitis were Peptostreptococcus spp., Propionibacterium spp., Prevotella spp., and Fusobacterium spp. This review describes the microbiology, diagnosis, and management of ocular infections due to anaerobic bacteria in children.
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