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Updated: Jul 6, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Higher order aberrations in children with amblyopia.

Caitriona Kirwan¹, Michael O'Keefe

¹The Children's University Hospital, Dublin, Ireland.

Journal of Pediatric Ophthalmology and Strabismus

|April 15, 2008

Summary

Higher order aberrations were similar in the eyes of children with amblyopia and their normal counterparts. These findings suggest higher order aberrations do not significantly contribute to the development of amblyopia.

Area of Science:

Ophthalmology
Pediatric Ophthalmology
Vision Science

Background:

Amblyopia, or "lazy eye," affects visual development.
Its causes include strabismus (eye misalignment) and anisometropia (unequal refractive error).
The role of higher order aberrations in amblyopia remains unclear.

Purpose of the Study:

To quantify and characterize higher order aberrations in children with amblyopia.
To compare these aberrations between amblyopic eyes and fellow normal eyes.
To investigate the potential contribution of higher order aberrations to amblyopia development.

Main Methods:

Utilized the iTrace Visual Function Analyzer to measure higher order aberrations.
Studied 30 children (ages 6-17) with unilateral amblyopia (15 strabismic, 15 anisometropic).

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The Measurement and Treatment of Suppression in Amblyopia

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

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The Measurement and Treatment of Suppression in Amblyopia

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

Compared aberration metrics between amblyopic and normal fellow eyes.

Main Results:

No statistically significant differences were found in total higher order aberrations between amblyopic and normal eyes.
Specific aberration types (coma, spherical, astigmatism, trefoil, 3rd-6th order terms) showed no significant differences.
Mean root mean square values for aberrations were comparable across groups.

Conclusions:

Higher order aberrations are similar in amblyopic eyes (strabismic or anisometropic) and normal fellow eyes.
Unlike lower order aberrations (sphere, cylinder), higher order aberrations are unlikely to be a primary factor in amblyopia development.
Further research may explore other visual pathway mechanisms in amblyopia.