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Updated: Jul 6, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Skin metastasis during follow-up of a clear cell renal carcinoma]
R Martínez-Rodríguez1, F Rodríguez-Escovar, A Bujons Tur
1Servicio de Urología Fundació Puigvert, Barcelona, España. hugomar2@yahoo.es
Objective:
To report a new case of metastatic renal carcinoma with atypical localization. Skin metastatic involvement by urological tumors is a rare clinical entity. It is usually associated with internal organ involvement, so that this finding makes prognosis poor. We review the most frequent metastatic sites, their prognostic implications and treatment.
Methods:
We present the case of a 60-year-old male patient with the diagnosis of inferior maxillary skin metastasis 18 months after radical nephrectomy for clear cell adenocarcinoma.
Results:
The patient was treated with oral Sorafenib within a phase II clinical trial. Two years after diagnosis the patient is alive and a disease-free.
Conclusions:
The wide variability of localizations and forms of presentation of metastatic renal carcinoma obliges to be alert during followup. New antiangiogenic drugs are an efficient therapeutic option.
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