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Updated: Jul 6, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
The role of users in innovation in the pharmaceutical industry
Ruud E H M Smits1, Wouter P C Boon
1Department of Innovation Studies, Copernicus Institute for Sustainable Development and Innovation, Faculty of Geo-sciences, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands. r.smits@geo.uu.nl
Abstract:
Traditionally, innovation in the pharmaceutical industry is organised according to the linear model. Over the past two decades this model lost its meaning as a result of rising costs, increased competition, new scientific developments and better-informed, more demanding users. The linear model is not well equipped to involve these new actors and to include their feedback. Starting from a systemic approach, the involvement of actors in pharmaceutical innovation processes, more in particular users, is put central. It is discussed and illustrated with three cases why a systemic model may be more effective to cope with present developments and why users should be involved. To wind up, conclusions are drawn regarding the implications of a systemic approach for policymakers, researchers and firms.
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