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Updated: Jul 6, 2026

Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis
Published on: July 3, 2015
Cytoplasmic-nuclear trafficking of steroid hormone receptors
1Hormones and Reproduction Research Unit, INSERM 135, Faculty of Medicine, South Paris, 94275 Le Kremlin Bicêtre, France.
Abstract:
The nuclear localization of most steroid hormone receptors reflects a dynamic process: the receptor constantly diffuses out of the nucleus and is reimported by an active mechanism. The outward movement from the nucleus of the receptors and of other nuclear proteins is also mediated by the nuclear localization signals.
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