Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of the COVID-19 Pandemic on Outpatient Visit-Based Frequency Trends of Herpes Zoster Ophthalmicus.

Cureus·2026

Same author

Preoperative Use of the Rho Kinase Inhibitor Ripasudil Protects the Corneal Endothelium from Trabeculectomy-Induced Damage.

Clinical ophthalmology (Auckland, N.Z.)·2026

Same author

Prospective natural history and clinical biomarkers of EYS-associated retinopathy in the KEYS study.

Scientific reports·2026

Same author

Reduction in Pigment Epithelial Detachment Thickness with Faricimab versus Aflibercept 2 mg during Head-to-Head Dosing in TENAYA/LUCERNE.

Ophthalmology science·2026

Same author

Ocular pharmacokinetics of tivozanib eye drops in patients with neovascular age-related macular degeneration: comparison with phase 1 trials of oral tivozanib in solid tumors.

International journal of retina and vitreous·2026

Same author

Choriocapillaris Flow Deficits Impact Macular Neovascularization Risk in Long-Term Follow-Up for Central Serous Chorioretinopathy.

Clinical ophthalmology (Auckland, N.Z.)·2026

Search research articles

Related Experiment Video

Updated: Jul 6, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Polypoidal choroidal vasculopathy and treatments.

Fumi Gomi¹, Yasuo Tano

¹Department of Ophthalmology, Osaka University Medical School, Osaka, Japan. fgomi@ophthal.med.osaka-u.ac.jp

Current Opinion in Ophthalmology

|April 15, 2008

Summary

Polypoidal choroidal vasculopathy (PCV) is a distinct condition from age-related macular degeneration, with photodynamic therapy showing promise but recurrence impacting long-term vision. Further treatments are needed to inhibit its vascular development.

Related Experiment Videos

Last Updated: Jul 6, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Area of Science:

Ophthalmology
Vascular Biology
Medical Diagnostics

Background:

Polypoidal choroidal vasculopathy (PCV) presents unique choroidal vascular abnormalities.
PCV prevalence is notably higher in Asian populations compared to Caucasians.

Purpose of the Study:

To review current knowledge on the clinical characteristics of PCV.
To assess available treatments for PCV.

Main Methods:

Diagnosis relies heavily on Indocyanine green angiography.
Comparative efficacy of treatments like photodynamic therapy and bevacizumab was evaluated.

Main Results:

Photodynamic therapy demonstrates efficacy in treating PCV, with superior 1-year outcomes compared to age-related macular degeneration treatments.
Recurrence of PCV after photodynamic therapy significantly impacts long-term visual outcomes.
Bevacizumab shows limited efficacy for PCV.

Conclusions:

Clinical characteristics and differential responses to treatment suggest PCV is a separate entity from age-related macular degeneration, despite shared genetic factors.
While photodynamic therapy offers encouraging results for PCV, the risk of recurrence necessitates ongoing monitoring and management.
Development of novel therapeutic strategies to inhibit the exudative choroidal vasculature in PCV is crucial.