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Progress towards completing the human linkage map
1Department of Human Genetics, Yale University School of Medicine, New Haven, Connecticut 06510.
Current Opinion in Genetics & Development
|June 1, 1991
Abstract:
Genetic linkage maps order polymorphic loci (markers) along a chromosome and provide a measure of distance that is an inherently statistical measure of the frequency of meiotic recombination and has no simple relationship to DNA length in Mb. Few accurate and dense maps now exist. Maps with markers spaced every 2 cM providing accurate estimates of distance should be available in the next few years, however.