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Molecular genetic approaches to the cytoskeleton in Dictyostelium
B Patterson1, K M Ruppel, J A Spudich
1Department of Cell Biology, Stanford University, CA 94305.
Current Opinion in Genetics & Development
|October 1, 1991
Abstract:
Recent advances in molecular genetic techniques are being applied in Dictyostelium to test and expand prevailing views on the functioning of the actin-based cytoskeleton. Current research involves the disruption, by homologous recombination, of genes encoding cytoskeletal elements. We suggest combining classical and molecular genetic approaches to supplement these investigations.