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Updated: Jul 6, 2026

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
Published on: October 3, 2016
[Biologic risk due to accident in academic personnel]
1Dipartimento di Medicina Ambientale e Sanità Pubblica, Università di Padova, Via Giustiniani 2, 35128 Padova. elisabettadavanzo@libero.it
Abstract:
Needlestick injuries since 2004 to 2006 were evaluated in University healthcare workers that reported an accident by point, sharp or mucosal contamination. During this period, 497 accidents with instruments contamined with biological fluids were reported. The injuries were most frequent between 9 a.m. and 1 p.m. (233 accidents). There is no difference during the week (excluding Saturday and Sunday), whereas February, May, June, and July were the months at risk. The most of accidents were during the first four hours of the job. They were identified 423 known sources and compliance with follow-up was evaluated. Only 26.3% of subjects injured with known hepatitis B source, 32.3% with known HIV source, and 40% with known HCV source completed follow-up. Fortunately, no seroconversion was observed. The lack of compliance with the follow-up, also if the source is known, needs to stimulate healthcare workers to subject to the protocols and to follow the standard procedure to prevent the needlestick injuries.
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