Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Mats01:25

Microbial Mats

Microbial communities forming biofilms and mats represent complex, spatially structured ecosystems where metabolic processes are stratified according to light, oxygen, and nutrient gradients. Biofilms are initial colonization stages, only a few millimeters thick, while mature microbial mats can reach centimeter-scale thickness and display intricate vertical organization. Their structural and functional heterogeneity allows microorganisms to occupy distinct ecological niches within a few...
Microbial Nutrition01:28

Microbial Nutrition

Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
Metabolism of Chemolithotrophs01:15

Metabolism of Chemolithotrophs

Chemolithotrophs are microorganisms that obtain energy by oxidizing inorganic molecules such as hydrogen gas (H₂), ammonia (NH₃), reduced sulfur compounds (H₂S, S²⁻), and ferrous iron (Fe²⁺). Unlike heterotrophic organisms that rely on organic carbon, chemolithotrophs transfer electrons from these inorganic donors to the electron transport chain (ETC), generating a proton motive force (PMF) that drives ATP synthesis through oxidative phosphorylation. However, because inorganic electron donors...
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
Hyperthermophilic Bacteria01:21

Hyperthermophilic Bacteria

Domain Bacteria includes some unique hyperthermophilic species. They exhibit remarkable adaptations that enable survival in extreme environments.Thermotoga species are rod-shaped, gram-negative, non-sporulating hyperthermophiles that form a sheath-like envelope called a toga. They ferment sugars or starch, producing lactate, acetate, CO₂, and H₂, and can also grow via anaerobic respiration using H₂ and ferric iron. Found in hot springs and hydrothermal vents, over 20% of their genes show strong...
Microbes and Methanogenesis01:26

Microbes and Methanogenesis

Methanogenesis is a critical microbial process in anaerobic ecosystems responsible for the biological production of methane, a potent greenhouse gas and valuable biofuel. This metabolic pathway is primarily facilitated by methanogenic archaea, which thrive in anoxic environments such as wetlands, sediments, and animal gastrointestinal tracts. The absence of oxygen in these habitats prevents aerobic respiration, thereby favoring alternative biochemical pathways for organic matter degradation.In...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is milk a conduit for developmental signals?

Advances in experimental medicine and biology·2002
Same author

Pulsatile exocytosis is functionally associated with GnRH gene expression in immortalized GnRH-expressing cells.

Endocrinology·2001
Same author

4-Hydroxytamoxifen differentially exerts estrogenic and antiestrogenic effects on discrete subpopulations of human breast cancer cells.

Endocrine·2001
Same author

Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells: dual control by intrinsic cellular pulsatility and gap junctional communication.

Endocrinology·2001
Same author

Spontaneous calcium oscillatory patterns in mammotropes display non-random dynamics.

Cell calcium·2000
Same author

Development of a destabilized firefly luciferase enzyme for measurement of gene expression.

BioTechniques·2000

Related Experiment Video

Updated: Jul 5, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

Mammosomatotropes: current status and possible functions.

L S Frawley1

  • 1Division of Cellular and Molecular Endocrinology at the Department of Anatomy and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

Trends in Endocrinology and Metabolism: TEM
|September 1, 1989
PubMed
Summary

Mammosomatotropes, cells secreting growth hormone and prolactin, are prevalent in pituitary tissue. These cells may act as transitional cells during development and in adults for hormone interconversion.

More Related Videos

Purification of the M. magneticum Strain AMB-1 Magnetosome Associated Protein MamAΔ41
11:07

Purification of the M. magneticum Strain AMB-1 Magnetosome Associated Protein MamAΔ41

Published on: March 25, 2010

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
11:07

High-Throughput Metabolic Profiling for Model Refinements of Microalgae

Published on: December 4, 2021

Related Experiment Videos

Last Updated: Jul 5, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

Purification of the M. magneticum Strain AMB-1 Magnetosome Associated Protein MamAΔ41
11:07

Purification of the M. magneticum Strain AMB-1 Magnetosome Associated Protein MamAΔ41

Published on: March 25, 2010

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
11:07

High-Throughput Metabolic Profiling for Model Refinements of Microalgae

Published on: December 4, 2021

Area of Science:

  • Endocrinology
  • Cell Biology
  • Pituitary Gland Research

Background:

  • Mammosomatotropes, dual hormone-secreting cells, are increasingly recognized in normal pituitary glands.
  • Understanding the role of these cells is crucial for pituitary development and function.

Purpose of the Study:

  • To investigate the prevalence and proposed transitional role of mammosomatotropes.
  • To elucidate the function of dual growth hormone and prolactin secretors in pituitary physiology.

Main Methods:

  • Analysis of normal pituitary tissue.
  • Cellular and molecular characterization of hormone-secreting cells.

Main Results:

  • Mammosomatotropes are common in normal pituitary tissue.
  • Evidence suggests these cells function as transitional intermediates.

Conclusions:

  • Mammosomatotropes play a key role in pituitary cell differentiation during development.
  • These cells facilitate functional plasticity, enabling interconversion between growth hormone and prolactin secretion in adults.