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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Where does obsessive-compulsive disorder belong in DSM-V?
Eric A Storch1, Jonathan Abramowitz, Wayne K Goodman
1Department of Psychiatry, University of Florida, Gainesville, Florida, USA. estorch@ufl.edu
The proposed reclassification of obsessive-compulsive disorder (OCD) into obsessive-compulsive spectrum disorders (OCSDs) is premature. Current empirical data on clinical presentation, neurobiology, and treatment response do not support this diagnostic shift.
Area of Science:
- Psychiatry
- Neuroscience
- Clinical Psychology
Background:
- A proposed reclassification of obsessive-compulsive disorder (OCD) into obsessive-compulsive spectrum disorders (OCSDs) is under debate for the DSM-V.
- This shift involves grouping OCD with related conditions under a broader diagnostic umbrella.
Purpose of the Study:
- To critically analyze empirical data concerning the proposed nosological shift of OCD into OCSDs.
- To review shared commonalities and differences between OCD and putative OCSDs.
Main Methods:
- Literature review of empirical research.
- Analysis of data on clinical presentation, phenotype, neurobiology, and treatment response.
Main Results:
- The available data reveal significant shared characteristics but also notable differences between OCD and proposed OCSDs.
- Empirical evidence does not currently substantiate a distinct OCSD spectrum separate from OCD.
Conclusions:
- The proposed reclassification of OCD into a separate OCSD spectrum is premature.
- Current empirical data do not support this diagnostic and conceptual change for the DSM-V.
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