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Outcome of younger patients with acute diverticulitis
F Hjern1, T Josephson, D Altman
1Division of Surgery, Danderyd Hospital, Stockholm, Sweden. fredrik.hjern@ds.se
Insights
Younger patients experiencing acute diverticulitis are not more prone to severe complications. However, recurrence rates for acute diverticulitis were slightly higher in younger individuals compared to older patients.
Area of Science:
- Gastroenterology
- Surgical Gastroenterology
Background:
- Controversy exists regarding whether younger patients with acute diverticulitis face higher complication and recurrence risks.
- This study addresses the clinical outcomes of acute diverticulitis in relation to patient age.
Purpose of the Study:
- To investigate if a younger age at the primary episode of acute diverticulitis is associated with increased complications and recurrence.
- To compare the severity and progression of acute diverticulitis in patients aged 50 years or less versus those older than 50.
Main Methods:
- A review of 234 patients with a primary episode of acute diverticulitis was conducted.
- Diagnosis was confirmed via computed tomography (CT) and/or pathology.
- Follow-up data, including postal questionnaires, were collected over a mean period of 30 months.
Main Results:
- No significant differences in fever or white blood cell count were observed between younger (<50 years) and older (>50 years) patient groups.
- Younger patients had a lower rate of severe diverticulitis on CT (2% vs. 11.9%, P=0.025).
- While recurrence rates were slightly higher in younger patients (25% vs. 19.5%), the difference was not statistically significant (P=0.423).
Conclusions:
- The initial presentation of acute diverticulitis does not appear to be more aggressive in patients aged 50 years or less.
- Slightly higher recurrence rates of diverticulitis were noted in younger patients, though not significantly different.
Background:
There is controversy over whether patients presenting with a primary attack of acute diverticulitis at a younger age are more prone to complications and recurrence than older patients.
Methods:
A review, including postal questionnaires, was undertaken of 234 patients who had a primary episode of acute diverticulitis. The diagnosis was confirmed by computed tomography (CT) and/or pathology report. The mean length of follow-up was 30 (range 16-45) months.
Results:
In 58 patients aged 50 years or less no differences in fever or white blood cell count were found in comparison with findings in 176 patients aged above 50 years. The rate of severe diverticulitis observed with CT was lower in the younger patients (2 versus 11.9 per cent; P = 0.025). Surgical management during the first admission was undertaken less commonly in younger patients (2 versus 6.8 per cent; P = 0.271). Rates of subsequent events (recurrent diverticulitis and/or further surgery) during follow-up were higher in younger patients (25 versus 19.5 per cent), but this was not significant (P = 0.423). A type II error cannot be excluded.
Conclusion:
First episodes of acute diverticulitis were not more aggressive in patients aged 50 years or less. Recurrence rates were slightly higher than in older patients.
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