Related Experiment Video
Updated: Jul 5, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
Published on: August 2, 2019
Controlled non-heart beating organ donation: neither the whole solution nor a step too far
Insights
Controlled non-heart beating organ donation faces ethical and legal challenges in the UK. Recent legislation supports donation after cardiac death by emphasizing patient autonomy and best interests.
Area of Science:
- Intensive Care Medicine
- Transplantation Ethics
- Organ Donation Law
Background:
- Clinicians in UK intensive care units express concerns about controlled non-heart beating organ donation.
- Established programs contribute significantly to cadaveric donations annually.
- Ethicolegal obstacles hinder the successful implementation of these donation programs.
Purpose of the Study:
- To address ethicolegal obstacles in controlled non-heart beating organ donation.
- To examine the conflict between end-of-life care decisions and organ donation approaches.
- To clarify legal uncertainties regarding organ retrieval timing after cardiac death.
Main Methods:
- Analysis of ethicolegal considerations in organ donation.
- Review of legislative changes impacting end-of-life care and organ donation.
- Examination of clinical practices in controlled non-heart beating donation programs.
Main Results:
- Key areas of concern include potential conflicts of interest, legality of adjusting end-of-life care for donation, and timing of organ retrieval.
- Recent legislative changes provide a foundation for donation after cardiac death.
- Emphasis on patient autonomy and best interests is crucial.
Conclusions:
- Controlled non-heart beating organ donation requires local resolution of ethicolegal issues.
- New legislation supports donation after cardiac death, prioritizing patient autonomy.
- Addressing clinician concerns is vital for expanding organ donation.
Abstract:
While many intensive care clinicians in the UK continue to express significant concerns regarding controlled non-heart beating organ donation, others are involved in established programmes that make an increasingly significant contribution to the total number of cadaveric donations each year. The successful introduction of a controlled non-heart beating organ donation programme requires local resolution of any apparent ethicolegal obstacles to the process, with specific attention needing to be given to three areas: the potential conflict of interest between decision making over futility and any subsequent approach regarding organ donation; a belief that it may be unlawful to adjust in any way an end of life care pathway in order to allow donation to take place, and, finally, an uncertainty over how soon after cardiac death organ retrieval can begin. It is proposed that recent changes in legislation provide, through an emphasis on patient autonomy and best interests, a solid ethicolegal foundation for donation after cardiac death.
More Related Videos
Related Concept Videos
Kidney Transplant I: Introduction
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

