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Updated: Jul 5, 2026
09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
[Acute renal function deterioration in a Coronary Unit in Spain].
1Servicio de Cardiología, Hospital Ramón y Cajal, Madrid, España. docalcala@hotmail.com
Medicina Intensiva
|April 17, 2008
Summary
Acute renal function deterioration (ARFD) affects 26% of patients with acute heart disease, significantly increasing in-hospital mortality risk. Early recognition of ARFD is crucial for managing cardiac patients.
Area of Science:
- Cardiology
- Nephrology
- Critical Care Medicine
Context:
- Assesses acute renal function deterioration (ARFD) in patients admitted with acute heart disease.
- Utilizes data from a tertiary university hospital's Coronary Care Unit.
- Employs a retrospective study design with 100 consecutive patients from 2004.
Purpose:
- To determine the incidence of ARFD in acute heart disease patients.
- To evaluate the prognostic significance of ARFD on in-hospital mortality.
- To identify factors associated with ARFD in this population.
Summary:
- The incidence of ARFD was 26%, characterized by a mean serum creatinine increase of 1.5 mg/dl.
- ARFD was significantly linked to older age, hypertension, and chronic kidney disease.
- Patients with ARFD experienced more complex hospital stays, longer admissions, and higher mortality (33% vs. 6%).
Impact:
- Highlights ARFD as a frequent and critical complication in acute heart disease.
- Underscores the association between ARFD and increased mortality, emphasizing the need for vigilant monitoring.
- Provides evidence for the prognostic value of ARFD in predicting outcomes for cardiac patients.
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