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Updated: Jul 5, 2026

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution
Published on: April 16, 2019
Clinical resolution of glycogenic hepatopathy following improved glycemic control
Rachel M Hudacko1, Aram V Manoukian, Stephen H Schneider
1Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School-UMDNJ, New Brunswick, NJ 08903, USA. hudackra@umdnj.edu
Abstract:
Glycogenic hepatopathy is an underrecognized complication of long-standing poorly controlled diabetes mellitus. It is characterized by abnormal glycogen accumulation in hepatocytes, elevated liver enzymes and hepatomegaly. This is a distinct entity from other causes of hepatomegaly and elevated liver enzymes in diabetics such as nonalcoholic fatty liver disease. It is important to distinguish this entity as it has the potential for resolution following improved glycemic control as described by this case report.
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