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[Treatment of chronic hepatitis B with interferon alfa-2b (Intron A)]
J Cianciara1, T Laskus, H Hryniewicz
1Klinika Hepatologii Zakaźnej Instytutu Chorób Zakaźnych i Pasozytniczych AM, Warszawie.
Przeglad Epidemiologiczny
|January 1, 1991
Abstract:
Eighteen patients with biopsy proven chronic hepatitis B and markers of ongoing viral replication were treated with interferon alpha-2b (Intron A) while 24 similar patients served as control group. Permanent termination of HBV replication and normalization of ALT and AST activity was seen in 7 (39%) treated patients and in only two (8%) controls (p less than 0.05). Adverse reactions were few and subsided with the termination of therapy. These results of interferon therapy in chronic hepatitis B seem encouraging.