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Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
[Neuro- and psychophysiology of pain in children.]
1Abteilung für Physiologie des Zentralnervensystems, II. Physiologisches Institut der Universität, Im Neuenheimer Feld 326, D-6900, Heidelberg.
Insights
Children, including newborns, feel pain, contrary to past beliefs. Their pain perception and reactions differ from adults due to developmental stages, necessitating careful pediatric pain management.
Area of Science:
- Pediatric Pain Management
- Neuroscience
- Developmental Psychology
Context:
- Historical underestimation of children's pain sensitivity due to immature nervous system theories.
- Shift in understanding, supported by recent literature and scientific congresses, acknowledging pain in all pediatric age groups.
- Recognition of developmental differences in pain experience and cognitive evaluation between children and adults.
Purpose:
- To challenge outdated notions of pediatric pain insensitivity.
- To highlight the fully developed sensory pain system at birth in humans and mammals.
- To underscore the importance of understanding age-related pain responses and management.
Summary:
- The sensory pain system is fully functional at birth, with observable pain reactions in infants.
- Children's pain experience evolves with cognitive development, influencing expression and evaluation.
- Nociceptive and malfunction-related pain are common in children, while neuropathic pain is less frequent.
Impact:
- Informs pediatricians about the reality of pain in children, advocating for appropriate treatment of acute and chronic pain.
- Emphasizes the need for tailored pain management strategies considering children's developmental stages.
- Contributes to improved clinical practices and reduced suffering in pediatric patients.
Abstract:
In the past the view has often been expressed that children are less sensitive to pain than adults as a result of the assumption that their nervous system is not as well developed. According to this theory, newborns were not supposed to feel pain at all, and for this reason minor surgery was often performed with inadequate anesthesia. Evidence in the more recent literature and the regular choice of "pain in children" as a topic for congresses exemplify the more and more widespread belief that children of all ages can feel pain and, relative to their developmental stage, suffer accordingly. However, there are significant differences in the way children experience and react to pain in comparison to adults, e.g., because of the difference in ability to evaluate acute or chronic pain cognitively. At birth, all human sensory organs have developed far enough to be full functional-as a result of the long gestational period, which is far longer than most other mammalian species. The results of animal experiments and observations in newborns have led to the conclusion that in humans and other mammals, the sensory pain system is fully developed at birth. Pain-related reactions can be seen in the motor, vegetative and endocrine pain parameters, and in the infant's crying. As the experience of pain increases, conditioned avoidance reactions can be noted, as can the child's experience of psychosomatic pain reinforcement by the care-givers, e.g., when a crying child in pain receives more attention from the persons around it. In pre-school children, the level of pain can be measured using appropriate instruments, as demonstrated in cases of chronic arthritis. As cognition develops further, the patient's own concept of health and sickness changes, as does the ability to express feelings of pain. In the pathogenesis of pain in children, the dominant types are nociceptor pain (e.g., as a result of trauma or infection) and pain resulting from malfunction (e.g., physical malposition, migraine), whereas nervous pain occurs less frequently. Pediatricians should pay particular attention to the treatment of acute and chronic pain in children.
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