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Bilateral endogenous panophthalmitis caused by Salmonella typhi: first case report
Orbit (Amsterdam, Netherlands)
|April 17, 2008
Summary
This study reports the first case of metastatic bilateral panophthalmitis caused by Salmonella typhi in a young male. Despite treatment, the severe eye infection led to bilateral phthisis bulbi.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Metastatic bilateral endogenous panophthalmitis is a rare and severe ocular condition.
- Prompt diagnosis and treatment are crucial for managing sight-threatening infections.
Observation:
- A young male presented with fever, proptosis, and vision loss in both eyes.
- Systemic examination revealed bronchopneumonia, with Salmonella typhi identified in blood cultures.
- Ocular examination and imaging confirmed bilateral panophthalmitis.
Findings:
- The patient received intravenous antibiotics and underwent core vitrectomy with intravitreal antibiotics in the right eye.
- Systemic treatment resolved bronchopneumonia, proptosis, and periorbital edema.
- Despite treatment, the patient developed bilateral phthisis bulbi, indicating irreversible ocular damage.
Implications:
- This case highlights Salmonella typhi as a causative agent of metastatic bilateral panophthalmitis.
- It underscores the importance of considering systemic infections in the differential diagnosis of bilateral panophthalmitis.
- Early recognition and aggressive management are essential, though visual outcomes can be poor.
