[Effect of lymphostimulation on lymphatic drainage of the rat lower limb in central lymphostasis]

To evaluate functional status of rat hindleg lymphatic drainage in dynamic experiments, Wistar rats were divided into three groups: control, experimental and a group exposed to induced lymphostimulation. Central lymphostasis was provoked in experimental and lymphostimulation group. The latter group was also exposed to lymphotropic lymphostimulation. Functional status of the lymphatic drainage was assessed by the time of appearance of the marker (methylene blue) injected into the rat paw. The results indicate that lymphatic drainage and a carrier function of the lymph node were suppressed in the experimental group during the observation time. Lymphostimulation in the third group corrected the above disorders by experiment day 30. Thus, lymphostimulation can be an alternative method of management of the central lymphostasis syndrome in clinical practice.