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[Antibiotic resistance in enterococci isolated from gastrointestinal tract of long-livers]

I L Harmasheva, N K Kovalenko

    Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993)
    |April 18, 2008
    PubMed

    Insights

    Enterococcal strains from long-livers showed high resistance to many antibiotics. While 9% were susceptible, most strains exhibited intermediate or full resistance to therapeutically important antibiotics.

    Area of Science:

    • Microbiology
    • Antimicrobial Resistance
    • Gut Microbiome

    Context:

    • Enterococci are common gut bacteria.
    • Long-lived populations may harbor unique microbial profiles.
    • Antibiotic resistance is a growing global health concern.

    Purpose:

    • To assess the antibiotic susceptibility of enterococcal strains isolated from long-livers.
    • To determine the prevalence of resistance to clinically important antibiotics in this population.

    Summary:

    • Antibiotic susceptibility testing was performed on 58 enterococcal strains from long-livers using the disk diffusion method.
    • A wide range of 47 antibiotics, including 16 clinically significant ones, were tested.
    • Results indicated that 79% of strains were resistant to 1-7 antibiotics, 12% showed intermediate susceptibility, and only 9% were fully susceptible to clinically relevant antibiotics.

    Impact:

    • This study provides baseline data on enterococcal antibiotic resistance in a unique population.
    • Findings may inform strategies for managing infections in elderly or immunocompromised individuals.
    • Highlights the potential for gut microbiota in long-livers to harbor antibiotic-resistant bacteria.

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