Related Experiment Video
Updated: Jul 5, 2026
08:02
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Occupational contact dermatitis due to essential oils.
Akiva Trattner1, Michael David, Aneta Lazarov
1Department of Dermatology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel. atrattner@clalit.org.il
Contact Dermatitis
|April 18, 2008
Summary
Occupational allergic contact dermatitis from essential oils is understudied. Patch testing is crucial for diagnosing and managing this condition, helping patients avoid specific allergens and protect their careers.
Area of Science:
- Dermatology
- Occupational Health
- Toxicology
Background:
- Allergic contact dermatitis (ACD) from essential oils (EOs) in occupational settings is not well-documented.
- Essential oils are increasingly used in various industries, raising concerns about potential workplace sensitization.
Observation:
- A case series of 5 patients with occupational ACD due to EOs was observed over two years.
- These cases add to the 11 previously reported instances in the medical literature.
Findings:
- Patch testing with standard, fragrance, and specific EOs is essential for accurate diagnosis.
- Identifying specific EO allergens is key to preventing further reactions.
Implications:
- Patients must strictly avoid identified EO allergens to prevent recurrence.
- Sensitization to EOs can significantly impact an individual's occupational future and career choices.
Related Concept Videos
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:23Hand hygiene
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
01:21Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
01:30Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
01:10PPE Use in Healthcare Settings II: Doffing
The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...