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Related Experiment Videos

Waist circumference and mortality.

Annemarie Koster1, Michael F Leitzmann, Arthur Schatzkin

  • 1Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA. kostera@mail.nih.gov

American Journal of Epidemiology
|April 18, 2008
PubMed
Summary
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Increased waist circumference is linked to higher mortality risk, even with a normal body mass index (BMI). This finding highlights the importance of waist size as an independent mortality predictor.

Area of Science:

  • Epidemiology
  • Public Health
  • Clinical Medicine

Background:

  • Waist circumference is an indicator of abdominal obesity.
  • Body mass index (BMI) is a common measure of adiposity.
  • The independent contribution of waist circumference to mortality risk requires further investigation.

Purpose of the Study:

  • To examine the association between waist circumference and all-cause mortality.
  • To investigate the combined effects of waist circumference and BMI on mortality.
  • To determine if increased waist circumference is an independent risk factor for mortality.

Main Methods:

  • Prospective cohort study of 154,776 men and 90,757 women aged 51-72 years.
  • Follow-up for all-cause mortality over 9 years (1996-2005).

Related Experiment Videos

  • Statistical analysis adjusted for BMI and other covariates.

    • Main Results:

    • Large waist circumference was associated with a ~25% increased mortality risk, independent of BMI.
    • This association persisted across various subgroups (disease status, smoking, race/ethnicity).
    • Individuals with normal BMI but large waist circumference had a ~20% higher mortality risk.

    Conclusions:

    • Increased waist circumference is a significant risk factor for mortality.
    • Waist circumference provides additional prognostic information beyond BMI.
    • Measuring waist circumference should be considered in mortality risk assessment.