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Updated: Jul 5, 2026

Reliable and High Efficiency Extraction of Kidney Immune Cells
Published on: August 19, 2016
Regulatory immune cells in kidney disease
V W S Lee1, Y M Wang, Y P Wang
1Centre of Transplant and Renal Research, Westmead Millennium Institute at University of Sydney, Australia. vincent_lee@wmi.usyd.edu.au
Abstract:
Lymphocytes and macrophages act as effector immune cells in the initiation and progression of renal injury. Recent data have shown that subpopulations of these immune cells (regulatory T lymphocytes and alternately-activated or regulatory macrophages) are potent modulators of tissue injury and repair in renal disease. Recent animal studies examining the therapeutic effect of these cells raise the exciting possibility that strategies targeting these cell types may be effective in treating and preventing kidney disease in humans. This review will describe their biological role in experimental kidney disease and therapeutic potential in clinical nephrology.
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