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Updated: Jul 5, 2026
08:46
A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)
Published on: March 7, 2017
Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma
Daphne A Haas-Kogan1, Anuradha Banerjee, Mehmet Kocak
1University of California, San Francisco, San Francisco, CA, USA. hkogan@radonc17.ucsf.edu
Neuro-Oncology
|April 18, 2008
Abstract:
The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem glioma (BSG). Children >or=3 and
