Related Experiment Video
Updated: Jul 5, 2026
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Wilm's Tumor in Children: A 10-year Experience from the Eastern Province of Saudi Arabia
1Department of Pediatrics, King Fahd Hospital of the University, King Faisal University, Al Khobar, Saudi Arabia.
Insights
Wilm's tumor is a curable childhood cancer, even in advanced stages. This study in Saudi Arabia shows high survival rates with current treatment protocols.
Area of Science:
- Pediatric Oncology
- Nephrology
- Cancer Research
Background:
- Wilm's tumor is the most common primary malignant tumor of the kidney in children.
- Early diagnosis and treatment are crucial for improving patient outcomes.
- Understanding treatment efficacy in different regions is important for global health.
Purpose of the Study:
- To evaluate the treatment outcomes and survival rates of pediatric patients with Wilm's tumor.
- To assess the effectiveness of National Wilm's Tumor Study protocols in a Saudi Arabian population.
- To analyze the impact of tumor stage and histology on patient prognosis.
Main Methods:
- Retrospective review of 18 children diagnosed with Wilm's tumor between 1985-1994.
- Analysis of patient demographics, tumor staging, histological findings, and treatment protocols.
- Calculation of disease-free survival rates based on follow-up data.
Main Results:
- The study included 18 children (8 males, 10 females) with a median age of 2.5 years.
- Tumor stages ranged from I to V, with 94% having favorable histology.
- An overall disease-free survival of 88.8% was achieved, with 2 deaths during follow-up.
Conclusions:
- Wilm's tumor is a highly curable malignancy in children, even in advanced stages.
- Treatment according to National Wilm's Tumor Study guidelines yields favorable survival rates.
- This study highlights the successful management of Wilm's tumor in Saudi Arabia.
Abstract:
Eighteen children with biopsy-proven Wilm's tumor were diagnosed and treated between 1985-1994 at the King Fahd Hospital of the University, Alkhobar, Saudi Arabia. There were eight males and 10 females. The median age at diagnosis was 2.5 years. Two patients (11%) had stage I, six patients (33%) stage II, eight patients (44%) stage III and one patient each (6%) had stages IV and V respectively. Seventeen patients (94%) had favorable histology and one (6%) had anaplastic type. One patient had bilateral tumor and one had associated aniridia. Follow-up was from 2 to 10 years (mean:5 years). The treatment administered was according to the recommendations of the National Wilm's Tumor Study II and III. Two patients died resulting in an overall disease-free survival of 88.8%. Our study further confirms that Wilm's tumor is a curable malignancy even in advanced stage.