Chronic renal failure in children in asir region of saudi arabia
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1College of Medicine, King Saud University, Abha, Saudi Arabia.
Insights
Urinary system anomalies are the most common cause of chronic renal failure (CRF) and end-stage renal failure (ESRF) in children in Saudi Arabia. Early diagnosis and treatment of these conditions are crucial to reduce incidence.
Area of Science:
- Pediatric Nephrology
- Public Health
- Epidemiology
Background:
- Chronic renal failure (CRF) and end-stage renal failure (ESRF) pose significant health challenges in pediatric populations.
- Understanding the etiological factors and incidence rates of pediatric kidney diseases is crucial for effective public health strategies.
Purpose of the Study:
- To determine the incidence and causes of chronic renal failure (CRF) and end-stage renal failure (ESRF) in children in Saudi Arabia.
- To identify the most prevalent etiological factors contributing to pediatric kidney disease in the region.
Main Methods:
- Retrospective analysis of pediatric patients (aged 12 years and below) admitted with CRF or ESRF between June 1990 and June 1995.
- Data collection included patient demographics, diagnosis, and causative factors for renal failure.
Main Results:
- A total of 62 children were analyzed, with a mean annual incidence of 15.6 per million for CRF and 9.2 per million for ESRF.
- Urinary system anomalies were the leading cause of CRF (64.5%), particularly in younger children (≤6 years, 50.9%).
- Glomerulopathies were a significant cause, especially in older children (>6 years, 45%).
Conclusions:
- The study highlights a high annual incidence of pediatric CRF and ESRF in Saudi Arabia.
- Urinary system anomalies are the predominant cause of pediatric kidney disease in this region, emphasizing the need for early detection and intervention.
- Early diagnosis and treatment of congenital urinary tract anomalies can potentially decrease the incidence of pediatric CRF and ESRF.
Abstract:
Sixty two children aged 12 years or below, with chronic renal failure (CRF) were admitted to Asir Central Hospital, Saudi Arabia, in the period from June 1990 to June 1995. Of them, 39 (63%) were in CRF while 23 (37%) were in end-stage renal failure (ESRF) at the time of presentation giving a mean annual incidence for CRF of 15.6 and for ESRF of 9.2 per million children. The male to female ratio was 1.8:1. The mean age of the children was 5.5 years (age range 20 days to 12 years). Urinary system anomalies (including urinary tract anomalies) were the leading cause of CRF (64.5%) followed by gloraerulopathies (17.7%). In those who presented before the age of six years, SO.9% had CRF caused by urinary system anomalies (including inherited kidney anomalies such as polycystic disease) while such anomalies accounted for only 30% of CRF in children older than six years. Glomerulopathies were the leading cause (45%) of CRF in this latter group. We conclude that our mean annual incidence of CRF and ESRF is high and urinary system anomalies constitute the commonest cause among children in our region. Early diagnosis should therefore be encouraged to ensure early treatment of these anomalies, thus decreasing the incidence of CRF.
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