Chronic renal failure in children in asir region of saudi arabia

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Insights

Urinary system anomalies are the most common cause of chronic renal failure (CRF) and end-stage renal failure (ESRF) in children in Saudi Arabia. Early diagnosis and treatment of these conditions are crucial to reduce incidence.

Area of Science:

  • Pediatric Nephrology
  • Public Health
  • Epidemiology

Background:

  • Chronic renal failure (CRF) and end-stage renal failure (ESRF) pose significant health challenges in pediatric populations.
  • Understanding the etiological factors and incidence rates of pediatric kidney diseases is crucial for effective public health strategies.

Purpose of the Study:

  • To determine the incidence and causes of chronic renal failure (CRF) and end-stage renal failure (ESRF) in children in Saudi Arabia.
  • To identify the most prevalent etiological factors contributing to pediatric kidney disease in the region.

Main Methods:

  • Retrospective analysis of pediatric patients (aged 12 years and below) admitted with CRF or ESRF between June 1990 and June 1995.
  • Data collection included patient demographics, diagnosis, and causative factors for renal failure.

Main Results:

  • A total of 62 children were analyzed, with a mean annual incidence of 15.6 per million for CRF and 9.2 per million for ESRF.
  • Urinary system anomalies were the leading cause of CRF (64.5%), particularly in younger children (≤6 years, 50.9%).
  • Glomerulopathies were a significant cause, especially in older children (>6 years, 45%).

Conclusions:

  • The study highlights a high annual incidence of pediatric CRF and ESRF in Saudi Arabia.
  • Urinary system anomalies are the predominant cause of pediatric kidney disease in this region, emphasizing the need for early detection and intervention.
  • Early diagnosis and treatment of congenital urinary tract anomalies can potentially decrease the incidence of pediatric CRF and ESRF.

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