Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Tract Calculi VI: Surgical Management

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

Portal Hypertension

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...

Diseases of the Liver and Gallbladder

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Hepatic Drug Excretion: Enterohepatic Cycling

Hepatic Drug Excretion: Enterohepatic Cycling

Enterohepatic cycling involves the active secretion of drugs and their metabolites into the bile via transporters in the canalicular membrane of hepatocytes. This secretion is an integral part of the digestive process, releasing these substances into the gastrointestinal (GI) tract.
Post-release drugs and metabolites can be reabsorbed into the body from the intestine. For conjugated metabolites like glucuronides, reabsorption requires enzymatic hydrolysis by intestinal microflora. This...

Urinary Tract Calculi I: Introduction

Urinary Tract Calculi I: Introduction

Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Performance assessment of a ventilator developed for emergency use in a resource-constrained ICU setting during the COVID-19 pandemic.

Biomedical engineering online·2025

Same author

Genomic landscape of lung cancer in the young.

Frontiers in oncology·2022

Same author

Life-threatening DRESS syndrome with kidney damage following severe COVID-19 in a patient with Down syndrome.

BMJ case reports·2021

Same author

Evaluation of a Spanish language version of the Asthma Trigger Inventory.

The Journal of asthma : official journal of the Association for the Care of Asthma·2020

Same author

A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis.

BMC research notes·2019

Same author

[Characteristics of chronic obstructive pulmonary disease due to tobacco consumption in pneumology patients in lima and callao].

Revista peruana de medicina experimental y salud publica·2018

Search research articles

Related Experiment Videos

[Intrahepatic lithiasis].

Hernando Torres-Zevallos¹, Sergio Sánchez-Gambetta, Rolando Mendivil Zapata

¹Medicina Interna, Hospital Nacional Dos de Mayo, Lima, Peru.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru

|April 18, 2008

Summary

Intrahepatic bile duct stones are common, particularly in East Asia. Early diagnosis and thorough evaluation are crucial for managing these recurrent conditions, despite treatment challenges.

Related Experiment Videos

Area of Science:

Gastroenterology and Hepatology
Surgical Oncology

Background:

Intrahepatic bile duct stones (hepatolithiasis) represent a significant clinical challenge, especially prevalent in East Asian populations.
Recurrent episodes of obstructive jaundice and serious complications underscore the complexity of managing this condition.

Observation:

Two distinct cases are presented: a male patient with a history of repeated obstructive jaundice and a female patient experiencing recurrences and severe complications.
Both cases highlight the chronic and recurring nature of intrahepatic bile duct stones.

Findings:

The diagnostic and therapeutic journey for patients with hepatolithiasis is often protracted, involving multiple interventions.
High recurrence rates and the potential for severe complications complicate treatment strategies.

Implications:

Emphasizes the critical need for detailed patient evaluation and prompt diagnosis to optimize treatment outcomes for intrahepatic bile duct stones.
Effective management strategies must address the inherent challenges posed by the high recurrence rate and potential for serious complications associated with hepatolithiasis.