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Antigen Presenting Cells

Antigen Presenting Cells

The immune system is a complex network of cells and molecules that protects the body from foreign invaders. T cells, a type of white blood cell, play a crucial role in this process. They recognize and attack foreign substances, such as pathogens, that enter the body.
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Related Experiment Video

Updated: Jul 5, 2026

Analysis of Pulmonary Dendritic Cell Maturation and Migration during Allergic Airway Inflammation

Analysis of Pulmonary Dendritic Cell Maturation and Migration during Allergic Airway Inflammation

Published on: July 23, 2012

The dendritic cell in allergic conjunctivitis.

Bita Manzouri¹, Tom Flynn, Masaharu Ohbayashi

¹Institute of Ophthalmology, Moorfields Eye Hospital, London, UK.

The Ocular Surface

|April 18, 2008

Summary

This summary is machine-generated.

Dendritic cell subtypes are crucial in ocular allergies. Understanding their roles in the eye can improve treatments for allergic eye disease.

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A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

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Analysis of Pulmonary Dendritic Cell Maturation and Migration during Allergic Airway Inflammation

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A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Area of Science:

Immunology
Ophthalmology

Background:

Acquired immune responses are initiated by antigen presentation to T lymphocytes.
Antigen-presenting cell phenotype and tissue environment dictate immune response outcomes.
Dendritic cell subtypes' roles in ocular type I hypersensitivity are poorly understood.

Purpose of the Study:

To review current knowledge on dendritic cell subtypes in ocular allergy.
To explore their contribution to the pathophysiology of ocular surface hypersensitivity.
To compare ocular allergic reactions to those in other mucosal tissues.

Main Methods:

Review of human ocular allergy studies.
Analysis of murine models of ocular allergy.
Comparative analysis with allergic reactions in other mucosal tissues.

Main Results:

Dendritic cell subtypes play a significant role in ocular allergy.
Their phenotype and location influence the immune response on the ocular surface.
Ocular allergic responses share similarities with other mucosal tissues.

Conclusions:

Further research into dendritic cell subtypes is needed for ocular allergy.
This knowledge can inform therapeutic strategies for allergic eye disease.
Understanding ocular immune responses contributes to broader mucosal immunology.