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Cyst fluid cytology of cerebellar hemangioblastoma: a case report
Sharda Lallu1, Sarla Naran, David Palmer
1Department of Laboratory Services, Capital and Coast District Health Board, Wellington, New Zealand.
Hemangioblastoma, an uncommon central nervous system neoplasm, commonly located in the cerebellum and more rarely in the spinal cord. In this report, we described the cytologic features of a cerebellar hemangioblastoma in a 53-year-old man, present in cystic fluid obtained at cranioctomy. Cytologic preparations were characterized by well preserved, scattered dissociate, and occasional groups of stromal cells with round to oval nuclei, fine chromatin, and lacelike or granular, vacuolated eosinophilic cytoplasm with a foamy appearances. In addition, calcific material, endothelial-like cells, blood, and macrophages were seen. The radiologic impression, cytologic features, and location led us to suggest the possibility of hemangioblastoma. Subsequent histopathological material revealed the characteristic features of hemangioblastoma.
Hemangioblastoma, an uncommon central nervous system neoplasm, commonly located in the cerebellum and more rarely in the spinal cord. In this report, we described the cytologic features of a cerebellar hemangioblastoma in a 53-year-old man, present in cystic fluid obtained at cranioctomy. Cytologic preparations were characterized by well preserved, scattered dissociate, and occasional groups of stromal cells with round to oval nuclei, fine chromatin, and lacelike or granular, vacuolated eosinophilic cytoplasm with a foamy appearances. In addition, calcific material, endothelial-like cells, blood, and macrophages were seen. The radiologic impression, cytologic features, and location led us to suggest the possibility of hemangioblastoma. Subsequent histopathological material revealed the characteristic features of hemangioblastoma.
