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Related Experiment Videos

Plants against snake-bites.

W B Mors1

  • 1Núcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, Brasil.

Memorias Do Instituto Oswaldo Cruz
|January 1, 1991
PubMed
Summary

Compounds from Mandevilla velutina and Eclipta prostata show activity against snake venom. This research explores natural product potential for developing novel snakebite treatments.

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Pharmacological Screening of Plants Recommended by Folk Medicine as Snake Venom Antidotes; IV. Protection against Jararaca Venom by Isolated Constituents1.

Planta medica·1994

Area of Science:

  • Pharmacology
  • Ethnobotany
  • Toxicology

Background:

  • Snakebite envenomation is a significant global health issue, particularly in tropical and subtropical regions.
  • Traditional medicine often utilizes plant-derived compounds for treating various ailments, including snakebites.

Purpose of the Study:

  • To investigate the potential of small molecular weight compounds from Mandevilla velutina and Eclipta prostata as snakebite treatments.
  • To identify natural sources with bioactive compounds effective against snake venom.

Main Methods:

  • Extraction of small molecular weight compounds from Mandevilla velutina and Eclipta prostata.
  • In vitro or in vivo assays to evaluate the efficacy of extracted compounds against snake venom activity.

Main Results:

  • Compounds isolated from Mandevilla velutina demonstrated significant activity against snake venom.
  • Compounds isolated from Eclipta prostata also exhibited notable efficacy in neutralizing snakebite effects.

Conclusions:

  • Mandevilla velutina and Eclipta prostata are promising sources for novel snakebite therapeutics.
  • Further research into these plant compounds could lead to the development of effective antivenom agents.

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