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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Hormones Regulating Blood Glucose01:16

Hormones Regulating Blood Glucose

Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...

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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
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Published on: April 4, 2012

GP supply and obesity.

Stephen Morris1, Hugh Gravelle

  • 1University of Manchester, UK. stephen.morris@brunel.ac.uk

Journal of Health Economics
|April 19, 2008
PubMed
Summary
This summary is machine-generated.

More general practitioners (GPs) are linked to lower body mass index (BMI) in England. Increased GP supply correlates with reduced obesity, suggesting smaller patient lists improve health management.

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Area of Science:

  • Public Health
  • Health Services Research
  • Epidemiology

Background:

  • Obesity is a significant public health concern globally.
  • Understanding factors influencing body mass index (BMI) is crucial for effective interventions.
  • The role of primary care physician availability in managing population health requires further investigation.

Purpose of the Study:

  • To examine the association between the supply of general practitioners (GPs) and individual body mass index (BMI) in England.
  • To determine if increased GP availability impacts population BMI levels.
  • To explore the implications for obesity management within primary care settings.

Main Methods:

  • Individual-level BMI data were regressed against area-level GP supply (full-time equivalent GPs per 1000 population).
  • The analysis incorporated numerous individual and area-level covariates to control for confounding factors.
  • Instrumental variable regression, using area house prices and age-weighted capitation, addressed the endogeneity of GP supply.

Main Results:

  • A 10% increase in GP supply was associated with a mean reduction in BMI of approximately 1 kg/m².
  • This reduction represents about a 4% decrease relative to the mean BMI observed in the study population.
  • The findings indicate a statistically significant relationship between GP availability and lower BMI.

Conclusions:

  • Increased general practitioner supply is associated with reduced body mass index in the English population.
  • Policies aimed at increasing GP numbers or reducing patient list sizes may contribute to obesity management.
  • Enhancing primary care capacity could be a viable strategy for public health initiatives targeting obesity.