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Updated: Sep 14, 2026

A Visual Description of the Dissection of the Cerebral Surface Vasculature and Associated Meninges and the Choroid Plexus from Rat Brain
Published on: November 14, 2012
[Cerebral arteriovenous malformations (CAVM)]
F Lazzaroni-Fossati1, M Magnani, E Repetto
1Istituto di Purericultura e Medicina Neonatale, Università di Genova.
Insights
This study presents two infants with severe brain arteriovenous malformations and congestive heart failure. Early diagnosis and understanding age-related features are crucial for managing these critical conditions in newborns.
Area of Science:
- Pediatric Cardiology
- Neurology
- Medical Imaging
Background:
- Endocranic arteriovenous malformations (AVMs) are rare but serious vascular anomalies.
- Congestive cardiac failure in neonates can be caused by various factors, including AVMs.
- The vein of Galen aneurysm is a specific type of AVM with significant hemodynamic impact.
Observation:
- Two cases of neonates presenting with large endocranic AVMs and irreversible congestive cardiac failure are detailed.
- The first case involved a newborn with a large angioma.
- The second case involved a newborn with a large aneurysm of the vein of Galen.
Findings:
- Infants with large endocranic AVMs, including vein of Galen aneurysms, can develop severe, irreversible congestive cardiac failure.
- Age-related diagnostic features are critical for timely identification of these conditions.
- The presented cases highlight the severity and rapid progression of symptoms.
Implications:
- Early recognition of endocranic AVMs and associated cardiac compromise is vital for neonatal outcomes.
- Understanding the specific age-related clinical and imaging findings aids in prompt diagnosis.
- This review underscores the importance of a multidisciplinary approach in managing neonatal AVMs and heart failure.
Abstract:
Two infants with endocranic A-V malformations and irreversible picture of congestive cardiac failure are presented: the first is a newborn with a very large angioma, the second is a newborn with a large aneurysm of the vein of Galen. A review of the literature is presented: the salient age-related features required to make a diagnosis are discussed.
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