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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

RACK1 and CIS mediate the degradation of BimEL in cancer cells

Weizhou Zhang1, George Zhi Cheng, Jianli Gong

  • 1Department of Microbiology, Mount Sinai School of Medicine, New York, New York 10029, USA.

The Journal of Biological Chemistry
|April 19, 2008
PubMed

Keywords:
BimEL degradation mechanismsRACK1 cancer functionCIS ubiquitin ligase rolePaclitaxel resistance pathways

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