Related Experiment Video
Updated: Jul 5, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Non-invasive imaging of coronary artery disease
Jim Stirrup1, S Richard Underwood
1Royal Brompton and Harefield NHS Trust, London SW3 6NP.
Insights
Choosing the right non-invasive cardiac imaging test is crucial in cardiology. This review covers single photon emission computed tomography myocardial perfusion scintigraphy, positron emission tomography, and multi-detector computed tomography for effective patient care.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Non-invasive cardiac imaging is a rapidly growing area in cardiology.
- Selecting the appropriate imaging modality is essential and depends on the specific clinical question and available resources.
Purpose of the Study:
- To review the roles of three key non-invasive cardiac imaging techniques.
- To provide guidance on test selection based on clinical needs.
Main Methods:
- Review article synthesizing current literature.
- Focus on single photon emission computed tomography myocardial perfusion scintigraphy (SPECT MPS).
- Focus on positron emission tomography (PET).
- Focus on multi-detector computed tomography (MDCT).
Main Results:
- SPECT MPS is widely used for assessing myocardial perfusion.
- PET offers high diagnostic accuracy and quantification of myocardial blood flow.
- MDCT provides detailed anatomical information of coronary arteries and cardiac structures.
Conclusions:
- Each imaging modality has unique strengths and indications.
- Optimal test selection requires careful consideration of the clinical scenario and test availability.
- These non-invasive techniques are vital for diagnosing and managing cardiovascular diseases.
Abstract:
Non-invasive imaging of the heart is an expanding field in cardiology and appropriate test selection depends on the clinical question and test availability. This article reviews the role of single photon emission computed tomography myocardial perfusion scintigraphy, positron emission tomography and multi-detector computed tomography.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

