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Updated: Jul 5, 2026
06:48
CD Spectroscopy to Study DNA-Protein Interactions
Published on: February 10, 2022
Allostery: DNA does it, too
1James Graham Brown Cancer Center, University of Louisville, 529 South Jackson Street, Louisville, Kentucky 40202, USA. j.chaires@louisville.edu
ACS Chemical Biology
|April 22, 2008
Abstract:
Allostery is a central concept for understanding protein function and regulation. It is less well appreciated that DNA is allosteric, too, and that DNA conformational changes can by coupled to protein binding interactions on the DNA lattice. Allosteric DNA interactions are emerging as important features in the assembly of the molecular machines that regulate transcription.
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