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Relationship between left ventricular geometry and left ventricular systolic and diastolic functions in patients with

Murat Cayli1, Mehmet Kanadaşi, Onur Akpinar

  • 1Department of Cardiology, Faculty of Medicine, Cukurova University, Adana, Turkey. drcayli@yahoo.com

Echocardiography (Mount Kisco, N.Y.)
|April 22, 2008
PubMed

Insights

In chronic severe aortic regurgitation, the left ventricle

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Echocardiography

Background:

  • Chronic aortic regurgitation (AR) causes left ventricle (LV) volume overload and dilatation.
  • Disease progression involves myocardial fibrosis, apoptosis, and LV dysfunction.
  • Understanding the relationship between LV geometry and function is crucial.

Purpose of the Study:

  • To assess the relationship between left ventricle (LV) geometry and LV systolic and diastolic functions in patients with chronic severe aortic regurgitation (AR).

Main Methods:

  • Eighty-eight patients with chronic severe AR and 42 controls underwent echocardiography.
  • Left ventricle ejection fraction (LVEF), transmitral velocities, and annular velocities were measured.
  • Diastolic function was classified into normal, impaired relaxation, pseudonormalization, and restrictive patterns.

Main Results:

  • Left ventricle (LV) long- and short-axis diameters increased, while LV ejection fraction (LVEF) and annular systolic velocity (Sa) decreased progressively with worsening diastolic dysfunction.
  • LV long-axis diastolic diameter was independently associated with LV systolic and diastolic functions.
  • Patients with restrictive patterns showed significantly increased LV long-axis diastolic diameters and decreased LVEF and Sa velocity.

Conclusions:

  • Left ventricle (LV) long-axis diastolic diameter is a key indicator closely related to LV systolic and diastolic functions in chronic severe aortic regurgitation (AR).
  • This finding highlights the importance of LV geometry in assessing functional status in AR.
Abstract

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