Related Experiment Video
Updated: Jul 5, 2026
Scanning Dos and Don'ts: Using Magnetic Resonance Imaging in Awake Children Aged 3 to 5 Years to Assess Brain Structure and Function
Published on: March 10, 2026
Differences in effective connectivity between dyslexic children and normal readers during a pseudoword reading task:
V Quaglino1, B Bourdin, G Czternasty
1Efficience Cognitive Dans les Conduites Humaines d'Apprentissage et de Travail, Ecchat, EA 2092, Université de Picardie Jules-Verne, Amiens, France.
Purpose:
This fMRI study investigated phonological and lexicosemantic processing in dyslexic and in chronological age- and reading level-matched children in a pseudoword reading task.
Materials And Methods:
The effective connectivity network was compared between the three groups using a structural model including the supramarginal cortex (BA 40; BA: Brodmann area), fusiform cortex (BA 37) and inferior frontal cortex (BA 44/45) areas of the left hemisphere.
Results:
The results revealed differences in connectivity patterns. In dyslexic patients, in contrast with chronological age- and reading level-matched groups, no causal relationship was demonstrated between BA 40 and BA 44/45. However, a significant causal relationship was demonstrated between BA 37 and BA 44/45 both in dyslexic children and in the reading level-matched group.
Conclusions:
These findings were interpreted as evidence for a phonological deficit in developmental dyslexia.
