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Updated: Jul 5, 2026

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Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
Published on: June 20, 2014
Peptidomimetics, a synthetic tool of drug discovery
Josef Vagner1, Hongchang Qu, Victor J Hruby
1Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA.
Current Opinion in Chemical Biology
|April 22, 2008
Abstract:
The demand for modified peptides with improved stability profiles and pharmacokinetic properties is driving extensive research effort in this field. Many structural modifications of peptides guided by rational design and molecular modeling have been established to develop novel synthetic approaches. Recent advances in the synthesis of conformationally restricted building blocks and peptide bond isosteres are discussed.
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