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Synthesis of exemestane labelled with (13)C
Erminia Fontana1, Alberto Pignatti, Danilo Giribone
1Nerviano Medical Sciences, Viale Pasteur 10, 20014 Nerviano (MI), Italy. erminia.fontana@nervianoms.com
Steroids
|April 22, 2008
Abstract:
The synthesis of exemestane Aromasin, an irreversible steroidal aromatase inhibitor, specifically labelled with (13)C is reported. The preparation of [(13)C(3)]exemestane was achieved according to an eight-step procedure starting from the commercially available testosterone.
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