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Related Experiment Video

Updated: Jul 5, 2026

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
06:57

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Published on: November 11, 2021

Energy restriction results in a mass-adjusted decrease in energy expenditure in cats that is maintained after weight

Cecilia Villaverde1, Jon J Ramsey, Alice S Green

  • 1Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616-8741, USA.

The Journal of Nutrition
|April 22, 2008
PubMed
Summary

Dietary energy restriction (ER) in cats leads to a sustained decrease in energy expenditure (EE), even after weight regain. This metabolic adaptation may hinder long-term weight management in feline obesity.

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Area of Science:

  • Veterinary Medicine
  • Animal Nutrition
  • Metabolic Studies

Background:

  • Obesity is a common health issue in domestic cats.
  • Dietary energy restriction (ER) is a primary strategy for feline weight loss.
  • Current ER protocols often face challenges with sustained success and weight regain.

Purpose of the Study:

  • To investigate if ER causes a lasting reduction in mass-adjusted energy expenditure (EE) in cats.
  • To determine if this EE reduction opposes weight loss and promotes weight regain.
  • To understand the metabolic consequences of ER in feline obesity.

Main Methods:

  • 10 adult neutered cats were studied at three phases: obese baseline, during 40% ER for weight loss, and after weight regain.
  • Body weight (BW), body condition score (BCS), fat mass (FM), and total energy expenditure (EE) were measured.
  • Energy intake (EI) and energy balance were calculated for each phase.

Main Results:

  • Weight loss reduced BW, BCS, and FM significantly.
  • Total EE decreased during weight loss and remained lower than baseline even after weight regain.
  • Despite lower EE post-regain, energy intake was also reduced, leading to similar energy balance across phases.

Conclusions:

  • Energy restriction in cats results in a mass-adjusted decrease in energy expenditure.
  • This metabolic adaptation persists after weight regain, potentially contributing to difficulties in long-term feline weight management.
  • Further research is needed to optimize ER strategies for cats.