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Progressive encephalomyelopathy and cerebellar degeneration in a captive-bred snow leopard (Uncia uncia)

M F Stidworthy1, J C M Lewis, J Penderis

  • 1International Zoo Veterinary Group, Keighley Business Centre, South Street, Keighley, West Yorkshire BD21 1AG.

The Veterinary Record
|April 22, 2008
PubMed
Abstract

No abstract available in PubMed .

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DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...