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Updated: Jul 5, 2026

Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
[Rabies in Chile: 1989-2005]
Myriam Favi C1, Luis Rodríguez A, Carla Espinosa M
1Laboratorio Diagnóstico de Rabia, Instituto de Salud Pública de Chile, Santiago, Chile.
Rabies epidemiology in Chile (1989-2005) revealed a significant increase in bat rabies cases, particularly variant 4. This highlights the need for public education on responsible pet ownership to prevent bat-to-animal rabies transmission.
Area of Science:
- Veterinary Epidemiology
- Zoonotic Disease Surveillance
- Public Health
Context:
- Rabies poses a significant public health threat globally.
- Understanding rabies epidemiology is crucial for effective control strategies.
- Chile has experienced rabies cases in various animal reservoirs.
Purpose:
- To analyze the epidemiological trends of rabies in Chile from 1989 to 2005.
- To identify the primary animal reservoirs and circulating rabies variants.
- To assess the risk of rabies transmission to humans and domestic animals.
Summary:
- A retrospective study analyzed 39,793 national rabies registries.
- Positive cases included 719 bats, 7 dogs, 7 cats, 1 bovine, and 1 human.
- A significant increase in bat rabies positivity, predominantly variant 4, was observed.
Impact:
- Findings underscore the complex wild rabies cycle in Chile.
- Emphasizes the need for ongoing rabies control programs.
- Highlights the importance of public education for responsible pet ownership to mitigate zoonotic transmission risks.
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