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Related Experiment Video

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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

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Intermittent pneumatic compression for treating venous leg ulcers.

E A Nelson¹, R Mani, K Vowden

¹University of Leeds, School of Healthcare, Baines Wing, Leeds, UK, LS2 9UT. e.a.nelson@leeds.ac.uk

The Cochrane Database of Systematic Reviews

|April 22, 2008

Summary

Intermittent pneumatic compression (IPC) may improve venous leg ulcer healing compared to no compression. However, its effectiveness when added to bandages or used alone requires further investigation.

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Area of Science:

Vascular Medicine
Wound Healing
Medical Devices

Background:

Intermittent pneumatic compression (IPC) is a mechanical compression method for swollen limbs.
It is utilized in treating venous leg ulcers and lymphoedema-related swelling.
This review assesses the efficacy of IPC for venous leg ulcer treatment.

Purpose of the Study:

To evaluate if IPC enhances venous leg ulcer healing rates.
To determine the impact of IPC on the quality of life for venous leg ulcer patients.

Main Methods:

Searched multiple databases including Cochrane, MEDLINE, EMBASE, and CINAHL up to December 2007.
Included randomized controlled trials comparing IPC with control or different IPC regimens.
Data extraction and quality assessment were performed by two authors.

Main Results:

Seven trials involving 367 participants were identified; only one trial had robust methodology.
One trial showed significantly higher healing rates with IPC versus dressings (62% vs 28%).
Four trials comparing IPC plus compression to compression alone yielded mixed results; one showed benefit, three did not.

Conclusions:

IPC might enhance healing compared to no compression, but evidence is inconclusive when used with bandages or as a substitute.
Rapid IPC demonstrated superior healing over slow IPC in one trial.
Further research is needed to establish IPC's role in contemporary compression therapy for venous leg ulcers.