Related Experiment Video
Updated: Jul 5, 2026

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
Published on: June 26, 2018
Low level laser therapy for nonspecific low-back pain
R Yousefi-Nooraie1, E Schonstein, K Heidari
1Tehran University of Medical Sciences, Centre for Academic and Health Policies, P.O. Box 13145-967, Tehran, Iran. ryousefi@razi.tums.ac.ir
Low level laser therapy (LLLT) shows minor pain relief for low-back pain but lacks sufficient evidence for widespread clinical use. Further rigorous trials are needed to confirm its effectiveness and optimal application.
Area of Science:
- Biomedical Engineering
- Physical Therapy
- Pain Management
Background:
- Low-back pain (LBP) is a significant global health issue, leading to substantial medical costs and disability.
- Low level laser therapy (LLLT) is a therapeutic modality explored for managing musculoskeletal conditions, including LBP.
Purpose of the Study:
- To systematically evaluate the efficacy of LLLT in patients diagnosed with non-specific low-back pain.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (CENTRAL, MEDLINE, CINAHL, EMBASE, AMED, PEDro) up to November 2007.
- Seven randomized controlled trials (RCTs) of reasonable quality, investigating LLLT for non-specific LBP, were included in the analysis.
- Data extraction and quality assessment were performed independently by two reviewers following Cochrane Back Review Group guidelines.
Main Results:
- LLLT demonstrated statistically significant but clinically unimportant pain relief compared to sham therapy in sub-acute and chronic LBP patients.
- One study indicated LLLT's superiority over sham in reducing short-term disability.
- LLLT combined with exercise showed no additional benefit over exercise alone for pain or disability reduction.
- A reduced relapse rate was observed in the LLLT group at six-month follow-up, with no reported side effects.
Conclusions:
- Insufficient data exists to definitively conclude the clinical effectiveness of LLLT for low-back pain due to study heterogeneity.
- Further high-quality RCTs are recommended to investigate LLLT's effects against various comparators, treatment durations, and parameters.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
