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Published on: November 18, 2016
Reference values for some fundamental haemostatic factors in the dog
B Stefanon1, G Stefanon, E Righi
1Istituto di Produzione Animale, Universita degli Studi di Udine, Italy.
Polskie Archiwum Weterynaryjne
|January 1, 1991
Summary
This study establishes normal reference ranges for key blood clotting tests in dogs, including prothrombin time (PT) and activated partial thromboplastin time (APTT). These findings aid in interpreting canine haemostatic analysis for better clinical decisions.
Area of Science:
- Veterinary Medicine
- Haematology
- Clinical Pathology
Background:
- Accurate reference values for haemostatic parameters are crucial for diagnosing bleeding disorders in dogs.
- Existing reference ranges may vary, necessitating standardized data for clinical application.
Purpose of the Study:
- To define reliable reference values for basic haemostatic parameters in a healthy canine population.
- To establish normal ranges for prothrombin time (PT), activated partial thromboplastin time (APTT), coagulation factors VIII:C and IX:C, and platelet counts.
Main Methods:
- A methodological survey was conducted on 34 healthy dogs to determine baseline haemostatic values.
- Standard laboratory assays were used to measure PT, APTT, factors VIII:C and IX:C, and platelet counts.
- The derived reference values were subsequently applied to a larger cohort of 130 dogs.
Main Results:
- Established reference ranges: PT (6.5-9.5s), APTT (17.5-26.3s), Factor VIII:C (58-260%), Factor IX:C (67-163%), Platelets (185.8-354.4 x 10^9/L).
- Demonstrated the utility of these reference values in interpreting laboratory results from dogs undergoing clinical evaluation.
Conclusions:
- The study provides essential reference intervals for key canine haemostatic parameters.
- Accurate haemostatic analysis, guided by these values, assists in the precise interpretation of laboratory findings in veterinary diagnostics.
- These findings support improved clinical decision-making for dogs with potential coagulation abnormalities.
