[The diagnosis and treatment of lymphogranulomatosis in children]

Results of treatment of 124 pediatric patients with Hodgkin's disease with a follow-up period of not less than 5 years were analysed. The diagnostic workup included laparotomy. As a result, stage of disease was changed in 24 (28.5%) out of 84 operated patients. Treatment with CVPP combination chemotherapy (several cycles) and extended-field telegammatherapy yielded a five-year survival rate of 86.2% with 77.4% of patients being free from relapse. Splenectomy did not influence long-term results: five-year survival rates in operated and non-operated patients were 86.9 and 85%, respectively. No delayed toxicity associated with chemoradiation treatment was encountered.