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Related Experiment Video

Updated: Jul 5, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

[Multiple myeloma: past, present and future--editorial].

Xiao-Yan Ke, Yan-Fang Wang, Yu-Hua Yang

Zhongguo Shi Yan Xue Ye Xue Za Zhi

|April 23, 2008

Summary

This summary is machine-generated.

New therapies, including proteasome inhibitors and immunomodulatory agents, offer improved effectiveness for multiple myeloma treatment. These advances represent significant progress beyond conventional chemotherapy for this incurable plasma cell neoplasm.

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Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

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Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

Area of Science:

Hematology
Oncology
Cancer Biology

Background:

Multiple myeloma is a plasma cell neoplasm that is currently incurable with conventional chemotherapy.
Understanding myeloma biology and genetics has driven the development of novel therapeutic strategies.

Discussion:

Newer agents like proteasome inhibitors and immunomodulatory drugs show greater efficacy than traditional chemotherapy.
Combinational regimens are also emerging as effective treatment options.

Key Insights:

Novel drug classes are transforming multiple myeloma treatment paradigms.
Advances in understanding tumor formation have led to targeted therapies.

Outlook:

Continued research into myeloma biology promises further therapeutic innovations.
The development of more effective and less toxic treatments remains a key goal.